Searchable abstracts of presentations at key conferences in endocrinology

ea0086p221 | Metabolism, Obesity and Diabetes | SFEBES2022

Pregnancy following islet cell transplantation in a woman with type 1 diabetes and autoimmune Addison’s disease

Birrell Kayleigh , Ali Mudassir , Shaw James , MacDougall Malcolm , Williams Simon , Napier Catherine

A 33-year-old woman with type 1 diabetes and autoimmune Addison’s disease conceived in September 2021 following careful preconception counselling. The patient had a history of recurrent, severe hypoglycaemia requiring intensive care admission and had previously received two allogenic islet cell transplants (January 2020 and November 2020). The patient had no severe hypoglycaemia following transplantation, although she continued to experience overnight hypoglycaemia, while...

ea0056gp69 | Cardiovascular | ECE2018

Can monogenic severe hypertriglyceridemia be differentiated from polygenic forms through clinical features: data from APPROACH and COMPASS studies in FCS and non-FCS hypertriglyceridemic patients?

O'Dea Louis , MacDougall James , Digenio Andres , Hubbard Brant , Arca Marcello , Moriarty Patrick , Kastelein John , Bruckert Eric , Witztum Joseph

Introduction: Differentiation between familial chylomicronemia syndrome (FCS), a rare hypertriglyceridemia, and severe hypertriglyceridemia (sHTG; non-FCS) is challenging due to overlap in triglyceride (TG) levels and symptomology but important in disease management. Clinical characteristics that allow for reliable differentiation may exist in the presenting clinical features and primary diagnostic testing. The objective of this analysis was to assess whether readily obtainabl...